UPS said just before 6:30 p.m. that there were three crew members on board the plane, but it has not confirmed any injuries or casualties.
The Federal Aviation Administration shared the following statement about the crash:
“UPS Flight 2976 crashed around 5:15 p.m. local time on Tuesday, Nov. 4, after departing from Louisville Muhammad Ali International Airport in Kentucky. The McDonnell Douglas MD-11 was headed to Daniel K. Inouye International Airport in Honolulu. The FAA and NTSB will investigate. The NTSB will lead the investigation and will provide all updates. This information is preliminary and subject to change.”
Louisville Metro Police Department and multiple other agencies are responding to the crash near Fern Valley and Grade Lane, police confirmed on X.
Injuries have been reported.
A shelter-in-place has been ordered for everything within five miles of the airport, and people have been ordered to stay away due to active fire and debris.
Videos from the scene show a large plume of black smoke from the scene and fire.
Louisville UPS Plane Crash A plume of smoke wafts over airport property after reports of a plane crash at Louisville International Airport, Tuesday, Nov. 4, 2025, in Louisville, Ky. (AP Photo/Jon Cherry) (Jon Cherry/AP)
APTOPIX Louisville UPS Plane Crash A fireball erupts near airport property after reports of a plane crash at Louisville International Airport, Tuesday, Nov. 4, 2025, in Louisville, Ky. (AP Photo/Jon Cherry) (Jon Cherry/AP)
Louisville Plane Crash A fiery plane crash is sending plumes of smoke into the sky in Louisville. (WLKY)
Louisville Plane Crash A fiery plane crash is sending plumes of smoke into the sky in Louisville. (WLKY)
Louisville Plane Crash A fiery plane crash is sending plumes of smoke into the sky in Louisville. (WLKY)
Louisville Plane Crash A fiery plane crash is sending plumes of smoke into the sky in Louisville. (WLKY)
Louisville Plane Crash A fiery plane crash is sending plumes of smoke into the sky in Louisville. (WLKY)
Louisville Plane Crash A fiery plane crash is sending plumes of smoke into the sky in Louisville. (WLKY)
Louisville Plane Crash A fiery plane crash is sending plumes of smoke into the sky in Louisville. (WLKY)
Louisville Plane Crash A fiery plane crash is sending plumes of smoke into the sky in Louisville. (WLKY)
UPS plane crashes on takeoff from Louisville, Kentucky, airport, igniting huge fire on ground A UPS plane crashed on takeoff from the airport in Louisville, Kentucky, igniting a huge fire on the ground, officials said Tuesday. (NBC/WAVE)
UPS Louisville Plane Crash A UPS plane has crashed in Louisville, prompting a shelter-in-place for a five-mile radius. PHOTO: WLKY-TV
UPS Louisville Plane Crash A UPS plane has crashed in Louisville, prompting a shelter-in-place for a five-mile radius. PHOTO: WLKY-TV
UPS Louisville Plane Crash A UPS plane has crashed in Louisville, prompting a shelter-in-place for a five-mile radius. PHOTO: WLKY-TV
UPS Louisville Plane Crash A UPS plane has crashed in Louisville, prompting a shelter-in-place for a five-mile radius.
UPS Louisville Plane Crash A UPS plane has crashed in Louisville, prompting a shelter-in-place for a five-mile radius. PHOTO: WLKY-TV
UPS Louisville Plane Crash A UPS plane has crashed in Louisville, prompting a shelter-in-place for a five-mile radius. PHOTO: WLKY-TV
UPS Louisville Plane Crash A UPS plane has crashed in Louisville, prompting a shelter-in-place for a five-mile radius. PHOTO: WLKY-TV
UPS Louisville Plane Crash A UPS plane has crashed in Louisville, prompting a shelter-in-place for a five-mile radius.
UPS Louisville Plane Crash A UPS plane has crashed in Louisville, prompting a shelter-in-place for a five-mile radius.
UPS Louisville Plane Crash A UPS plane has crashed in Louisville, prompting a shelter-in-place for a five-mile radius. PHOTO: WLKY-TV
UPS Louisville Plane Crash A UPS plane has crashed in Louisville, prompting a shelter-in-place for a five-mile radius.
UPS Louisville Plane Crash A UPS plane has crashed in Louisville, prompting a shelter-in-place for a five-mile radius.
UPS Louisville Plane Crash A UPS plane has crashed in Louisville, prompting a shelter-in-place for a five-mile radius.
UPS Louisville Plane Crash A UPS plane has crashed in Louisville, prompting a shelter-in-place for a five-mile radius.
UPS Louisville Plane Crash A UPS plane has crashed in Louisville, prompting a shelter-in-place for a five-mile radius.
UPS Louisville Plane Crash A UPS plane has crashed in Louisville, prompting a shelter-in-place for a five-mile radius.
UPS Louisville Plane Crash A UPS plane has crashed in Louisville, prompting a shelter-in-place for a five-mile radius.
UPS Louisville Plane Crash A UPS plane has crashed in Louisville, prompting a shelter-in-place for a five-mile radius.
UPS Louisville Plane Crash A UPS plane has crashed in Louisville, prompting a shelter-in-place for a five-mile radius.
UPS Louisville Plane Crash A UPS plane has crashed in Louisville, prompting a shelter-in-place for a five-mile radius.
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